Endometrial health · Ultrasound + 31 blood markers + clinical review
Private Endometrium Health Check
A comprehensive £599 endometrial assessment combining pelvic ultrasound with detailed endometrial imaging, a 31-marker blood panel including HE4, a 30-minute GP consultation and pharmacist medication review in a coordinated two-visit pathway.
- Pelvic ultrasound
- 31-marker blood panel
- GP + Pharmacist review
What is included in the £599 Endometrium Health Check?
The package combines four core components: pelvic ultrasound with detailed endometrial assessment, a 31-marker comprehensive blood panel including HE4, a 30-minute GP consultation and a pharmacist medication review. Visit 1 is for ultrasound and blood tests; Visit 2 takes place after the results are available so your symptoms, imaging, bloods and medication can be considered together.
Four core components
A coordinated endometrial assessment
The package brings together structural imaging, laboratory information and clinical review rather than relying on a single measurement or marker.
Pelvic Ultrasound
Transabdominal and, where clinically appropriate with consent, transvaginal ultrasound focused on endometrial thickness, echotexture, cavity appearances, uterus and ovaries.
31-Marker Blood Panel
Comprehensive haematology, kidney, liver, metabolic, iron, thyroid and related health markers, including HE4 as an adjunct tumour-associated marker.
30-Minute GP Consultation
Results-based review of bleeding pattern, symptoms, age, medical history, risk factors, ultrasound and blood results.
Pharmacist Medication Review
Review of HRT, contraception, tamoxifen, anticoagulants, supplements and other medication relevant to bleeding or endometrial health.
31-marker comprehensive blood panel
Blood tests organised by clinical purpose
The source package groups its laboratory tests into broad health categories so anaemia, thyroid issues, metabolic factors and medication-related considerations can be reviewed alongside the ultrasound.
Haematology & inflammation
Full Blood Count with differential and ESR, particularly relevant when heavy bleeding, fatigue or anaemia are concerns.
Kidney & electrolytes
Sodium, Potassium, Chloride, Bicarbonate, Urea, Creatinine and eGFR.
Liver profile
Bilirubin, ALP, AST, ALT, GGT, Total Protein, Albumin and Globulin.
Muscle, bone & metabolic
LDH, CK, Calcium, Phosphate, Uric Acid, Glucose, Triglycerides and Cholesterol.
Iron, Ferritin & Thyroid
Iron, TIBC, Ferritin, Free T4 and TSH — useful context for heavy bleeding, fatigue and cycle change.
HE4 adjunct marker
HE4 is included in the source package but should not be treated as a stand-alone screening or diagnostic test. It must be interpreted with symptoms, imaging and clinical context.
Pelvic ultrasound
What is assessed during the endometrial scan?
The ultrasound focuses on the endometrium while also assessing the uterus, ovaries and surrounding pelvic structures relevant to abnormal bleeding or endometrial concerns.
Endometrial thickness
The lining is measured and interpreted in relation to age, cycle phase, bleeding pattern, menopausal status and HRT use.
Endometrial echotexture
Assesses whether the lining appears uniform or heterogeneous and whether there is a focal abnormality.
Polyps & focal lesions
Looks for intracavitary focal lesions that may represent polyps or submucosal fibroids and may require further assessment.
Uterus & fibroids
Assesses uterine size, shape, myometrium and fibroid number, size and relationship to the endometrial cavity.
Ovaries & adnexa
Both ovaries and visible adnexal structures are reviewed for cysts, masses and other relevant findings.
Pelvic free fluid
Any free fluid is assessed in the context of symptoms, cycle stage and other sonographic findings.
Who may consider it
Bleeding patterns and endometrial concerns
The source package is designed for a broad range of menstrual, postpartum, HRT and endometrial concerns, but urgent symptoms still need the appropriate NHS or specialist pathway.
Heavy menstrual bleeding
Heavy or prolonged periods can be associated with fibroids, polyps, adenomyosis, hormonal factors or other conditions.
Irregular bleeding
Intermenstrual bleeding or unpredictable bleeding may require ultrasound and clinical assessment.
Amenorrhoea
Absent periods outside pregnancy and menopause may have hormonal, structural or endocrine causes.
Postpartum bleeding concerns
Persistent bleeding after childbirth can require assessment for retained tissue or other postpartum causes.
HRT-related bleeding
Unscheduled bleeding on HRT should be interpreted according to the HRT regimen, duration and current clinical guidance.
Previous thickened endometrium
Follow-up may be required when an earlier scan showed an abnormal endometrial measurement or focal cavity finding.
Tamoxifen use
Bleeding or abnormal imaging while using tamoxifen requires appropriate clinical assessment rather than routine ultrasound surveillance alone.
Family or genetic risk
A significant family history, including possible Lynch syndrome, may warrant formal genetics or gynaecology risk assessment.
Two-visit workflow
Tests first — results-based review afterwards
The workflow is designed so the GP and Pharmacist review completed investigations rather than discussing symptoms without the test results.
Visit 1: pelvic ultrasound
Transabdominal and/or transvaginal pelvic ultrasound is completed according to clinical need and consent.
Visit 1: blood tests
Blood is taken for the 31-marker panel, including HE4.
Reports become available
The source pathway states ultrasound reporting within 24 hours and blood results typically within 3–5 working days.
Visit 2: GP + Pharmacist
The 30-minute GP consultation and medication review take place once the results are available, with referral planning when required.
Optional add-ons
Further imaging, hormone testing or tissue diagnosis when needed
You do not need to choose every add-on before booking. They can be selected when clinically appropriate after your symptoms and initial findings are reviewed.
Gynaecologist Appointment
Source package add-on: +£350 for specialist review of complex bleeding, suspicious imaging or other endometrial concerns.
3D Pelvic Ultrasound
Source package add-on: +£269 for improved uterine-cavity and coronal-plane assessment.
Endometrial Biopsy / Pipelle
Source package add-on: +£700 when tissue diagnosis is clinically indicated.
Hormone Profile
Source package add-on: +£240 for FSH, LH, Oestradiol and Progesterone.
AMH
Source package add-on: +£115 when ovarian reserve or fertility context is relevant.
MRI Pelvis / Vitamins
MRI Pelvis (£500–700 in the source package) and Vitamin D/B12/Folate (+£285) are also listed as optional add-ons.
Prompt assessment
Postmenopausal bleeding should not wait for routine reassurance screening
Current NICE guidance recommends a suspected-cancer pathway referral for unexplained postmenopausal bleeding in people aged 55 and over, and consideration of the same pathway for those under 55. A private health-check package should support — not delay — that assessment.
Postmenopausal bleeding
Any unexplained vaginal bleeding after menopause requires prompt clinical assessment, particularly when it cannot be attributed to expected HRT bleeding.
Persistent intermenstrual bleeding
Repeated bleeding between periods should be discussed with a clinician even if a previous scan was normal.
Heavy bleeding with dizziness or weakness
Seek urgent clinical care if bleeding is very heavy or associated with fainting, severe weakness, chest symptoms or marked shortness of breath.
Abnormal scan finding
Thickening, an intracavitary lesion or another suspicious finding may require gynaecology, hysteroscopy and biopsy rather than repeated ultrasound alone.
Before your appointment
How to prepare for the endometrial ultrasound
Preparation differs between the transabdominal and transvaginal parts of the pelvic examination.
Full bladder for transabdominal imaging
Follow your booking instructions; a comfortably full bladder usually improves the initial pelvic overview.
Empty bladder for transvaginal imaging
If an internal scan is clinically appropriate and you consent, you will normally empty your bladder first.
Bring previous results
Bring prior pelvic ultrasound, hysteroscopy, biopsy, MRI, blood-test or gynaecology results where available.
Bring medication details
Include HRT, contraception, tamoxifen, anticoagulants and supplements because they may influence bleeding or clinical interpretation.
Clinic locations
Endometrium Health Check in London and St Albans
Use the PrivateSono booking link below to view current appointment availability.
Central London
27 Welbeck Street
London, W1G 8EN — close to Harley Street and Marylebone.
Book Central LondonSt Albans
54–56 Victoria Street
St Albans, AL1 3HZ — convenient for Hertfordshire and surrounding areas.
Book St AlbansPatient questions
Endometrium Health Check FAQs
Answers about endometrial ultrasound, the 31-marker panel, HE4, two-visit workflow, urgent bleeding and optional add-ons.
Need help before booking? Call 020 7101 3377What is included in the £599 Endometrium Health Check?
The package includes four core components: pelvic ultrasound with an endometrial focus, a 31-marker comprehensive blood panel including HE4, a 30-minute GP consultation and a pharmacist medication review. It follows a two-visit workflow so the GP and pharmacist can review the completed ultrasound and blood results together.
What does the pelvic ultrasound assess?
The scan assesses endometrial thickness and appearance, the uterine cavity, fibroids, possible polyps, ovarian appearances and pelvic free fluid. It combines transabdominal imaging and, where clinically appropriate and consented to, transvaginal ultrasound for higher-resolution endometrial assessment.
What is included in the 31-marker blood panel?
The source package groups the tests into haematology and inflammation, kidney and electrolytes, liver profile, muscle and bone markers, metabolic markers, iron studies, ferritin, thyroid function and HE4. The results are interpreted in clinical context rather than as stand-alone screening tests.
What is HE4 and what does it mean?
HE4 is a tumour-associated marker that can contribute to risk assessment in selected gynaecological contexts. It is not a stand-alone screening or diagnostic test for endometrial or ovarian cancer. NICE ovarian-cancer guidance continues to use CA125 as the routinely recommended serum marker in the diagnostic pathway, so HE4 should be interpreted only alongside symptoms, imaging and clinical assessment.
Why is the package delivered in two visits?
Visit 1 is for the pelvic ultrasound and blood sampling. Once the ultrasound report and blood results are available, Visit 2 is arranged for the 30-minute GP consultation and pharmacist medication review so the results can be discussed together.
Who may consider an Endometrium Health Check?
The source package is intended for adults with amenorrhoea, irregular or heavy bleeding, intermenstrual bleeding, postpartum bleeding concerns, HRT-related bleeding, a known abnormal endometrial finding or a need for a more comprehensive endometrial assessment.
What should I do if I have postmenopausal bleeding?
Postmenopausal bleeding requires prompt clinical assessment and should not be treated as routine reassurance screening. Current NICE guidance recommends a suspected-cancer pathway referral for unexplained postmenopausal bleeding in people aged 55 and over, and consideration of the same pathway for those under 55.
Can this package diagnose or rule out endometrial cancer?
No. Ultrasound and blood markers can identify findings that need further investigation, but they cannot by themselves diagnose or exclude endometrial cancer. Suspicious bleeding or imaging may require gynaecology referral, hysteroscopy, endometrial biopsy or MRI.
How should I prepare for the pelvic ultrasound?
For the transabdominal part you will usually be asked to attend with a comfortably full bladder. If a transvaginal scan is clinically appropriate and you consent, you will normally empty your bladder before the internal examination. Follow the instructions supplied with your booking.
What optional add-ons are available?
The LondonSono source package lists a Gynaecologist appointment, 3D Pelvic Ultrasound, Endometrial Biopsy or Pipelle, a hormone profile, AMH, Vitamin D/B12/Folate testing and MRI Pelvis as optional add-ons when clinically appropriate.
Book online
Book your Private Endometrium Health Check
£599 for pelvic ultrasound, 31-marker blood panel including HE4, 30-minute GP consultation and pharmacist medication review.
Comprehensive endometrial assessment
Combine focused pelvic imaging, comprehensive blood tests and results-based clinical review
4 components • £599 • 2-visit workflow • Central London & St Albans